Rejuran skin healing treatment at The Rejuvenation Space Redfern
ServicesRejuran
Polynucleotide therapy — evidence-based

Services — Rejuran

Skin That Heals
From Within

Rejuran is an advanced skin healing treatment formulated with purified polynucleotides (PN) derived from salmon DNA. It works at the deepest layers of the skin to stimulate tissue repair, enhance elasticity, and restore the healthy, resilient quality that time and environmental exposure can gradually diminish.

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Regenerative Medicine

Beyond Surface
Correction

At The Rejuvenation Space in Redfern, Sydney, we are proud to offer Rejuran as part of our evidence-based approach to skin rejuvenation. This innovative treatment represents a shift in aesthetic medicine — moving away from simply filling or masking signs of ageing and towards genuine regeneration of the skin's own structure and function.

What if your skin could be encouraged to heal, regenerate, and renew itself from the cellular level? Rejuran does exactly that — working with your biology to stimulate real, meaningful change rather than relying on synthetic fillers or surface-level corrections.

Rejuran microinjection treatment at The Rejuvenation Space

How It Works

The Science of
Polynucleotides

Rejuran is an injectable treatment composed of polynucleotides — fragments of DNA derived from salmon. These biological molecules share a high degree of compatibility with human tissue, making them exceptionally well tolerated and biocompatible. When injected superficially into the dermis, polynucleotides interact with skin cells through a process known as adenosine A2A receptor activation, triggering a cascade of regenerative responses.

This activation stimulates fibroblasts — the cells responsible for producing collagen and elastin — to increase their activity. At the same time, Rejuran promotes angiogenesis (the formation of new blood vessels), which improves nutrient delivery and oxygenation within the skin. The treatment also supports the repair and reinforcement of the extracellular matrix — the structural scaffolding that gives skin its firmness and resilience.

Fibroblast activation

Stimulates the cells responsible for collagen and elastin production to increase their regenerative activity.

Angiogenesis

Promotes the formation of new blood vessels, improving nutrient delivery and oxygenation within the skin.

Extracellular matrix repair

Supports the structural scaffolding that gives skin its firmness, resilience, and youthful architecture.

Barrier restoration

Rebuilds hydration, thickness, and barrier function from within — not just at the surface.

Cellular regeneration science — Rejuran polynucleotide therapy

Treatment Indications

What Rejuran
Can Address

Rejuran is particularly well suited for those experiencing the early to moderate signs of skin ageing, as well as those with thin, dehydrated, or environmentally damaged skin.

Fine lines & wrinklesLoss of elasticity & firmnessRough or uneven skin textureUnder-eye thinning & crepinessCompromised skin barrierDullness & loss of radianceProactive skin preservationEnvironmentally damaged skin

The Rejuran Range

Formulations for
Every Concern

The Rejuran product family includes formulations tailored to different areas and concerns. Your clinician will recommend the most appropriate option based on your individual needs and treatment goals.

Rejuran Healer

Full face

The original formula, designed for overall facial rejuvenation and skin quality improvement. Addresses fine lines, elasticity, texture, and overall skin health across the face.

Rejuran I

Periorbital

Specifically formulated for the delicate periorbital area. Addresses fine lines, crepiness, and thinning skin around the eyes — a region that requires a gentler, more precise approach.

What to Expect

Your Rejuran
Treatment

01

Skin preparation

The skin is cleansed and a topical anaesthetic is applied for your comfort prior to treatment.

02

Microinjections

The polynucleotide solution is injected into the superficial dermis using a series of fine, precise microinjections across the treatment area.

03

Immediate aftercare

Small raised bumps at injection sites are normal and typically flatten within 24–48 hours. Mild redness and swelling usually resolve within a few days.

04

Progressive results

Most clients notice improvements in skin texture and hydration within the first two weeks, with continued improvement over the following months as collagen remodelling progresses.

30–45 min

Session length

2–3 sessions

Initial course

3–4 weeks

Between sessions

Recommended course

An initial course of two to three treatments spaced three to four weeks apart is generally recommended for optimal results, followed by maintenance sessions as advised by your clinician.

"Rejuran aligns beautifully with our philosophy at The Rejuvenation Space — a treatment that honours your skin's natural processes, working with your biology to stimulate real, meaningful change."

Rebecca — The Rejuvenation Space

Frequently Asked Questions

Rejuran
Questions Answered

Still have questions? [email protected]

Book in Redfern, Sydney

Restore Your Skin's
Natural Architecture

If you are seeking a treatment that goes deeper than the surface — that genuinely restores and revitalises your skin from within — Rejuran at The Rejuvenation Space may be the answer. Book your consultation today.